SlideCNA: spatial copy number alteration detection from Slide-seq-like spatial transcriptomics data
Abstract Solid 2000 bmw 528i front bumper tumors are spatially heterogeneous in their genetic, molecular, and cellular composition, but recent spatial profiling studies have mostly charted genetic and RNA variation in tumors separately.To leverage the potential of RNA to identify copy number alterations (CNAs), we develop SlideCNA, a computational